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Human studies of glucagon receptor antagonism show a striking result: hepatic amino-acid clearance drops hyperaminoacidaemia develops skeletal muscle becomes the fallback source of amino acids This pattern mirrors the very changes we see under GLP-1RA therapy
& Mojsov, S
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These work gently by increasing stool bulk or drawing water into the intestines, and are less likely to cause cramping or electrolyte disturbances when used as directed with adequate fluid intake
